ausgewählte Publikationen

Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, …, Teumer A, Medici M. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nat Commun. 2024; 15: 888.

Weihs A, Chaker L, Martin TC, Braun KVE, Campbell PJ, …, Teumer A. Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9. Thyroid Mar 2023. 301-311.

Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, …, Teumer A. Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021;12: 7174.

Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, …, Teumer A, Köttgen A. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nat Commun. 2021;12: 7173.

Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B, et al. KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI Insight. 2019;4.

Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, et al. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun. 2019;10: 4130.

Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, …, Teumer A, Köttgen A, Pattaro C. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019;51: 957–972.

Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019;51: 1459–1474.

Teumer A., Chaker L., Groeneweg S., Li Y., Di Munno C., Barbieri C., et al. Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nat Commun. 2018;9: 4455.

Teumer A. Common Methods for Performing Mendelian Randomization. Front Cardiovasc Med. Frontiers; 2018;5: 51.

Teumer A., Gambaro G., Corre T., Bochud M., Vollenweider P., Guessous I. et al. Negative effect of vitamin D on kidney function: a Mendelian randomization study. Nephrol Dial Transplant. 2018; 1-7.

Wild P.S., Felix J.F., Schillert A., Teumer A., Chen M.H. et al. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest. 2017;pii: 84840.

Teumer A., Qi Q., Nethander M., Aschard H., Bandinelli S., Beekman M. et al. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 2016;15: 811-24

Pattaro C., Teumer A., Gorski M., Chu A.Y., Li M., Mijatovic V. et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. Nature Publishing Group; 2016;7: 10023

Kasbohm E., Holtfreter B., Völker U., Petersmann A., Samietz S., Biffar R., Völzke H., Meisel P., Kacprowski T., Homuth G., Kocher T., Teumer A. Exome Variant Analysis of Chronic Perio-dontitis in 2 Large Cohort Studies. J Dent Res. SAGE Publications; 2016; 22034516665076

Teumer A., Schurmann C., Schillert A., Schramm K., Ziegler A., Prokisch H. Analyzing Illumina Gene Expression Microarray Data Obtained From Human Whole Blood Cell and Blood Monocyte Samples. Methods Mol Biol. 2016;1368: 85-97

Teumer A., Tin A., Sorice R., Gorski M., Yeo N.C., Chu A.Y. et al. Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Diabetes. 2016;65: 803-17

Auer P.L., Teumer A., Schick U., O’Shaughnessy A., Lo K.S., Chami N. et al. Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. Nat Genet. 2014;46: 629-34

Köttgen A., Albrecht E., Teumer A., Vitart V., Krumsiek J., Hundertmark C. et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013;45: 145-154

Teumer A.; Holtfreter B.; Völker U.; Petersmann A.; Nauck M.; Biffar R.; Völzke H.; Kroemer H.K.; Meisel P.; Homuth G.; Kocher T. Genome-wide association study of chronic periodontitis in a general German population. J Clin Periodontol. 2013 Nov;40(11):977-85

Westra H.J. et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet. 2013 Oct;45(10):1238-43

Teumer A.; Ernst F.D.; Wiechert A.; Uhr K.; Nauck M.; Petersmann A.; Völzke H.; Völker U.; Homuth G. Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0. BMC Genomics. 2013 Jul 26,14:506

Tozzi F.; Teumer A.; Munafò M; Rawal R. et al. A genomewide association study of smoking relapse in four European population-based samples. Psychiatr Genet. 2013 Aug,23(4):143-52

Köttgen, A.; Albrecht, E.; Teumer, A.; Vitart, V.; Krumsiek, J. et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 2013, 45(2), 145-54

Hek, K.; Demirkan, A.; Lahti, J.; Terracciano, A.; Teumer, A. et al. A Genome-Wide Association Study of Depressive Symptoms. Biological Psychiatry, 2013, pii: S0006-3223(12)00897-9

Schurmann, C. et al. Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS ONE, 2012, 7(12), e50938

Coviello, A. D. et al. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genetics, 2012, 8(7), e1002805

Rawal, R.; Teumer, A.; Völzke, H.; Wallaschofski, H.; Ittermann, T. et al. Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. Human Molecular Genetics, 2012, 21(14), 3275-82

Pattaro, C.; Köttgen, A.; Teumer, A.; Garnaas, M.; Böger, C. A. et al. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genetics, 2012, 8(3), e1002584

Zhai, G.; Teumer, A.; Stolk, L.; Perry, J. R. et al. Eight common genetic variants associated with serum DHEAS levels suggests a key role in ageing mechanisms. PLoS Genetics, 2011, 7(4), e1002025

Teumer, A.; Rawal, R.; Homuth, G.; Ernst, F. et al. Genome-wide Association Study Identifies Four Genetic Loci Associated with Thyroid Volume and Goiter Risk The American Journal of Human Genetics, 2011, 88(5):664-73

Kaplan, R. C.; Petersen, A.; Chen, M.; Teumer, A. et al. A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Human Molecular Genetics, 2010, 20(6), 1241-1251

Kolz, M.; Johnson, T.; Sanna, S.; Teumer, A.; Vitart, V. et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genetics, 2009, 5(6), e1000504

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